The fate of the wall crawler has been inextricably linked to that of the
brilliant Dr. Otto Octavius from the earliest career of both hero and villain.
As a brilliant nuclear physicist and cybernetics engineer, Octavius is without
peer; as Doctor Octopus he is a stunning criminal mastermind of prodigious
strength and unmatched viciousness. During his first encounter with Spider-Man,
he issued such a thorough pummeling to the hero that would become his arch-enemy
that the web slinger considered giving up the super hero game entirely.